Linifanib (ABT-869)

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Cat. No.: DIA-0230642

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	796967-16-3
Synonyms	AL39324,RG3635
Formula	C₂₁H₁₈FN₅O
Molecular Weight	375.41
SMILES	CC1=CC(=C(F)C=C1)NC(=O)NC2=CC=C(C=C2)C3=C4C(=N[NH]C4=CC=C3)N
Product Description	Linifanib (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, Flt-1/3 and PDGFRβ with IC50 of 4 nM, 3 nM, 3 nM/4 nM and 66 nM respectively, mostly effective in mutant kinase-dependent cancer cells (i.e. FLT3). Phase 3.

Format & Storage
Purity	> 97%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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