LDN-193189 2HCl

LDN-193189 2HCl

Cat. No.: DIA-0230659

Size: 50 mg Size: 500 mg Size: Customer Size
Product Information
CAS No. 1435934-00-1
Formula C25H23ClN6
Molecular Weight 479.4
SMILES Cl.C1CN(CCN1)C2=CC=C(C=C2)C3=C[N]4N=CC(=C4N=C3)C5=CC=NC6=C5C=CC=C6
Product Description LDN193189 HCl is the hydrochloride salt of LDN193189, which is a selective BMP signaling inhibitor, and inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM in C2C12 cell lines, respectively, 200-fold selectivity for BMP versus TGF-β.
Format & Storage
Purity > 97%
Shipping Shipped on dry ice.
Storage Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview Soluble in water and in DMSO
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