ISRIB (trans-isomer)

ISRIB (trans-isomer)

Cat. No.: DIA-0230702

Size: 50 mg Size: 500 mg Size: Customer Size
Product Information
CAS No. 1597403-47-8
Formula C22H24Cl2N2O4
Molecular Weight 451.34
SMILES ClC1=CC=C(OCC(=O)NC2CCC(CC2)NC(=O)COC3=CC=C(Cl)C=C3)C=C1
Product Description ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM and does not have global effects on translation, transcription, or mRNA stability in non-stressed cells.
Format & Storage
Purity > 98%
Shipping Shipped on dry ice.
Storage Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview Soluble in DMSO
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