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Cat. No.: DPP-001018
| Product Overview | |
|---|---|
| Species | Human, Mouse, Rat |
| Format | Lyophilized |
| Purity | ≥95% by SDS-PAGE |
| Target Information | |
|---|---|
| Gene Name | SPXN |
| UniProt No. | Q9BT56; D3Z752; M0R8L2; |
| Gene ID | 80763 |
| Molecular Formula | C74H114N20O19S |
| Molecular Weight | 1620 |
| Function | Spexin is a novel peptide hormone that is derived from the prohormone proNPQ and is conserved amongst mammalian species. Spexin (36-49) is post-translationally amidated with a C-terminal amidation processing signal motif (GRR) following Q49 residue of the pro-hormone. It contributes to CNS-mediated control of arterial blood pressure and salt and water balance and modulates nociceptive responses. Spexin reduces adipocyte uptake of long chain fatty acids and causes weight loss in rodents. Recently, it was suggested that this peptide may play a role in lipid and glucose metabolism in patients with type-2 diabetes mellitus. |
| Sequence | NWTPQAMLYLKGAQ-NH2 |
| Sequence | Asn-Trp-Thr-Pro-Gln-Ala-Met-Leu-Tyr-Leu-Lys-Gly-Ala-Gln-NH2 |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped on dry ice. |
| Storage | Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. |
Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
