Cat. No.: DCL-001023
| Product Information | |
|---|---|
| Parental | A549 |
| Organism | Human |
| Tissue | Lung |
| Target Name | TSC1 |
| Cell Type | Epithelial cells |
| Gender | Male |
| UniProt No. | Q92574 |
| Gene ID | 7248 |
| Gene Description | In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling. |
| Format | Frozen |
| Growth Properties | Adherent |
| Shipping & Storage | |
|---|---|
| Shipping | Cryopreserved on dry ice. |
| Storage Instructions | Store in liquid nitrogen. |
| Storage Buffer/Media | 8.7% Dimethylsulfoxide, 2% Cellulose, methyl ether |
