Human SRGN (Serglycin) knockout HeLa cell line

Human SRGN (Serglycin) knockout HeLa cell line

Cat. No.: DCL-001024

Size: 1 × 106 cells/vial Size: Customer Size
Product Information
Parental HeLa
Organism Human
Tissue Cervix
Target Name SRGN
Cell Type Epithelial cells
Gender Female
UniProt No. P10124
Gene ID 5552
Gene Description Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.
Format Frozen
Growth Properties Adherent
Shipping & Storage
Shipping Cryopreserved on dry ice.
Storage Instructions Store in liquid nitrogen.
Storage Buffer/Media 8.7% Dimethylsulfoxide, 2% Cellulose, methyl ether
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