Cat. No.: DCL-001089
Product Information | |
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Parental | HCT116 |
Organism | Human |
Tissue | Colon |
Target Name | PPARA |
Cell Type | Epithelial cells |
Gender | Male |
UniProt No. | Q07869 |
Gene ID | 5465 |
Gene Description | Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. |
Format | Frozen |
Growth Properties | Adherent |
Shipping & Storage | |
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Shipping | Cryopreserved on dry ice. |
Storage Instructions | Store in liquid nitrogen. |
Storage Buffer/Media | 8.7% Dimethylsulfoxide, 2% Cellulose, methyl ether |