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Cat. No.: DAA-001257
| Product Information | |
|---|---|
| Product Name | Human PON1 ELISA Kit |
| Species | Human |
| Description | Human PON1 ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human PON1 in serum, plasma and cell culture supernatants. This assay employs an antibody specific for Human PON1 coated on a 96-well plate. Standards and samples are pipetted into the wells and Human PON1 present in a sample is bound to the wells by the immobilized antibody. The wells are washed, and biotinylated anti-Human PON1 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of Human PON1 bound. |
| Sample Types | Cell Culture Supernatant, Serum, Plasma |
| Detection Range | 0.205 ng/mL - 50 ng/mL |
| Sensitivity | 0.2 ng/mL |
| Precision | Intra-assay precision CV ≤ 10.0%; Inter-assay precision CV ≤ 10.0% |
| Target Information | |
|---|---|
| Target Name | PON1 |
| UniProt No. | P27169 |
| Gene ID | 5444 |
| Target Description | Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. |
| Alternative Names | A esterase 1; A-esterase 1; Aromatic esterase 1; Arylesterase 1; Arylesterase B type; ESA; Esterase A; K 45; K-45; MVCD5; Paraoxonase; Paraoxonase 1; Paraoxonase B type; Paraoxonase, plasma; Paraoxonase1; PON; PON 1; PON1; PON1_HUMAN; Serum aryldiakylphosphatase; Serum aryldialkylphosphatase 1; Serum paraoxonase/arylesterase 1 |
| Shipping & Storage | |
|---|---|
| Sipping | Shipping on dry ice. |
| Storage | Store at -20°C. Please refer to protocols. |
Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
