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Cat. No.: DCL-001192
| Product Information | |
|---|---|
| Organism | Human (Normal) |
| Tissue | Human pancreatic tissue |
| Cell Type | Endothelial cells |
| Product Description | The pancreas is an endocrine gland and digestive organ which secretes hormones and produces pancreatic juice to aid in digestion.Pancreatic islets function as pancreatic endocrine cells to produce vital hormones such as glucagon, insulin, and amylin. Hence, Human Pancreatic Microvascular Endothelial Cells (HPaMEC) play a critical role to support the islet by transporting oxygen and nutrients to the pancreas, and affecting beta ell function and proliferation, influencing insulin gene expression during islet development, and product various growth factors. Additionally, HPaMEC are involved in optimizing blood glucose sensing and regulation. HPaMEC can be used an in vitro model for studying islet biology, pancreatic cancer, transplantation, and regenerative medicine. provides high quality HPaMEC, which are isolated from human pancreatic tissue and cryopreserved at P2 after purification, with ≥0.5 million cells in each vial. HPaMEC are characterized by immunofluorescence with antibodies specific to vWF/Factor VIII, VE-Cadherin and/or CD31 (PECAM). They are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HPaMEC can proliferate in Endothelial Cell Growth Medium (Cat# MD-0010), but they are not recommended for further expansion, because the purity of the endothelial population may decrease. |
| Gene Description | Human pancreatic tissue |
| Format | Frozen |
| Growth Properties | Adherent |
| Shipping & Storage | |
|---|---|
| Shipping | Cryopreserved on dry ice. |
| Storage Instructions | 37 °C, 95% Air, 5% CO2. Store in vapor phase of liquid nitrogen. |
| Storage Buffer/Media | Endothelial Cell Growth Medium |
Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
