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Cat. No.: DAA-001159
| Product Information | |
|---|---|
| Product Name | Human IL-1β ELISPOT Kit |
| Species | Human |
| Description | The ELISPOT assay is designed to enumerate cytokine producing cells in a single cell suspension. This method has the advantage of requiring a minimum of in-vitro manipulations allowing cytokine production analysis as close as possible to in-vivo conditions in a highly specific way. This technique is designed to determine the frequency of cytokine producing cells under a given stimulation, and the follow-up of such frequency during a treatment and/or a pathological state. Elispot assay constitutes an ideal tool in the TH1 / TH2 response, vaccine development, viral infection monitoring and treatment, cancerology, infectious diseases, autoimmune diseases and transplantation. Elispot assay is based on sandwich immuno-enzyme technology. Cell secreted cytokines or soluble molecules are captured by coated antibodies avoiding diffusion in supernatant, protease degradation or binding on soluble membrane receptors. After cell removal, the captured cytokines are revealed by tracer antibodies and appropriate conjugates. |
| Sample Types | Suspension Cells |
| Target Information | |
|---|---|
| Target Name | IL1B |
| UniProt No. | P01584 |
| Gene ID | 3553 |
| Target Description | Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. |
| Alternative Names | Catabolin; H1; IFNβ inducing factor; IL 1; IL 1β; IL-1β; IL1; IL1β; IL1B; IL1B_HUMAN; IL1F2; Interleukin 1β; Interleukin 1β precursor; interleukin 1, β; Interleukin-1β; OAF; Osteoclast activating factor; OTTHUMP00000162031; Preinterleukin 1β; Preinterleukinβ; Pro interleukin 1β |
| Shipping & Storage | |
|---|---|
| Sipping | Shipping on dry ice. |
| Storage | Store at +4°C. Please refer to protocols. |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
