Cat. No.: DCL-001156
| Product Information | |
|---|---|
| Parental | HCT116 |
| Organism | Human |
| Tissue | Colon |
| Target Name | EIF2AK3 |
| Cell Type | Epithelial cells |
| Gender | Male |
| UniProt No. | Q9NZJ5 |
| Gene ID | 9451 |
| Gene Description | Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1. |
| Format | Frozen |
| Growth Properties | Adherent |
| Shipping & Storage | |
|---|---|
| Shipping | Cryopreserved on dry ice. |
| Storage Instructions | Store in liquid nitrogen. |
| Storage Buffer/Media | 8.7% Dimethylsulfoxide, 2% Cellulose, methyl ether |
