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Cat. No.: DCL-001156
| Product Information | |
|---|---|
| Parental | HCT116 |
| Organism | Human |
| Tissue | Colon |
| Target Name | EIF2AK3 |
| Cell Type | Epithelial cells |
| Gender | Male |
| UniProt No. | Q9NZJ5 |
| Gene ID | 9451 |
| Gene Description | Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1. |
| Format | Frozen |
| Growth Properties | Adherent |
| Shipping & Storage | |
|---|---|
| Shipping | Cryopreserved on dry ice. |
| Storage Instructions | Store in liquid nitrogen. |
| Storage Buffer/Media | 8.7% Dimethylsulfoxide, 2% Cellulose, methyl ether |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
