x
- Home
- About Diabetes
- Services
- Diabetes Mellitus Modeling Solutions
- R&D Services for Diabetes Mellitus and Diabetic Complications
- By Drug Development Process
- About Us
- Careers
- Contact Us
Cat. No.: DPP-001125
| Product Overview | |
|---|---|
| Species | Human |
| Format | Lyophilized |
| Purity | ≥97% by SDS-PAGE |
| Nature | Synthetic |
| Target Information | |
|---|---|
| Gene Name | CCKAR |
| UniProt No. | P32238 |
| Gene ID | 886 |
| Alternative Names | CCK A; CCK A receptor; CCK AR; CCK-A receptor; CCK-AR; CCK1 R; CCK1-R; CCK1R; CCKA; CCKA receptor; CCKAR; CCKAR_HUMAN; CCKR Type A; CCKRA; Cholecystokinin 1 receptor; Cholecystokinin A receptor; Cholecystokinin receptor type A; Cholecystokinin type A receptor; Cholecystokinin-1 receptor |
| Function | Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| Cellular Localization | Cell membrane. |
| Sequence | RFLLPPNDVMQQSWH,Belongs to the G-protein coupled receptor 1 family. |
| Shipping & Storage | |
|---|---|
| Shipping | Shipped on dry ice. |
| Storage | Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
