GNE-477

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Cat. No.: DIA-0230813

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	1032754-81-6
Formula	C₂₁H₂₈N₈O₃S₂
Molecular Weight	504.63
SMILES	CC1=C(CN2CCN(CC2)[S](C)(=O)=O)SC3=C(N=C(N=C13)C4=CN=C(N)N=C4)N5CCOCC5
Target	mTOR
Product Description	GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with an IC50 of 4 nM for PI3Kα and Kiapp of 21 nM for mTOR.

Format & Storage
Purity	> 97%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.

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