Gedatolisib (PF-05212384, PKI-587)

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Cat. No.: DIA-0230843

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	1197160-78-3
Formula	C₃₂H₄₁N₉O₄
Molecular Weight	615.73
SMILES	CN(C)C1CCN(CC1)C(=O)C2=CC=C(NC(=O)NC3=CC=C(C=C3)C4=NC(=NC(=N4)N5CCOCC5)N6CCOCC6)C=C2
Target	PI3Kα, PI3Kγ and mTOR
Product Description	Gedatolisib (PF-05212384, PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR with IC50 of 0.4 nM, 5.4 nM and 1.6 nM in cell-free assays, respectively. Phase 2.

Format & Storage
Purity	> 99%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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