Treatment of gestational diabetes mellitus (GDM) aims to reverse hyperglycemia and reduce the risk of the associated adverse pregnancy outcomes. At the same time, pay attention to the safety of the therapy for mother and baby. Ace Therapeutics can provide researchers engaged in therapy development of GDM with more efficient function analysis and overall therapy services.
GDM is characterized by the inability of pancreatic β-cells to respond adequately to the increased insulin requirements of pregnancy resulting in varying degrees of hyperglycemia. Many risk factors for developing GDM are similar to those for type 2 diabetes, including obesity, family history of diabetes, and high-risk ethnicities. Additional risk factors include increased maternal age, fetal macrosomia, and personal history of GDM.
Organs Involved in The Pathophysiology of GDM (Jasmine, F. A.; et al. International Journal of Molecular Sciences. 2018)
Gestational diabetes is treated with a diabetic diet, exercise, medication (such as metformin), and sometimes insulin therapy. Management of GDM should occur in a multidisciplinary setting with joint diabetes and obstetric input. Most women can manage their GDM with dietary changes and exercise.
Therapy research provides more options for gestational diabetes treatment options. With the goal of scientific research of GDM, Ace Therapeutics can provide the therapy development services such as antidiabetics development (including insulin analog) and safety validation for gestational diabetes mellitus. Our services include but not limited to the followings.
 Insulin Analogs |
 Oral Agents |
| The rapid-acting insulin analogs and long-acting insulin analogs are effective in the treatment of GDM, but their safety has been controversial. Ace Therapeutics offers a full range of services for insulin analogs development, from target identification to drug optimization, providing in vitro and in vivo research assays. |
With the exception of metformin and glyburide, many oral agents that can be used for T2DM have not been fully validated in GDM. Ace Therapeutics offers a complete package of drugs development and safety validation services for oral agents of GDM to accelerate your drug development process. |
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Ace Therapeutics offers cost-effect and high-quality research services related to gestational diabetes mellitus therapy for our clients worldwide. Our assays are developed and processed with the highest standard and the results are delivered on time without compromising quality. Please feel free to contact us .
