GDC-0349

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Cat. No.: DIA-0230845

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	1207360-89-1
Synonyms	RG-7603
Formula	C₂₄H₃₂N₆O₃
Molecular Weight	452.55
SMILES	CCNC(=O)NC1=CC=C(C=C1)C2=NC(=C3CCN(CC3=N2)C4COC4)N5CCOCC5C
Target	mTOR
Product Description	GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.

Format & Storage
Purity	> 99%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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