EHT 5372

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Cat. No.: DIA-0243031

Size: 10 mg Size: 25 mg Size: 50 mg Size: 100 mg Size: Customer Size

Product Information
CAS No.	1425945-63-6
Formula	C₁₇H₁₁Cl₂N₅OS
Molecular Weight	404.27
SMILES	N=C(C(S1)=NC2=C1C3=C(NC4=CC=C(Cl)C=C4Cl)N=CN=C3C=C2)OC
Target	DYRK, CDK, GSK-3
Product Description	EHT 5372 is a highly potent and selective inhibitor of DYRK's family kinases with IC50s of 0.22, 0.28, 10.8, 93.2, 22.8, 88.8, 59.0, 7.44, and 221 nM for DYRK1A, DYRK1B, DYRK2, DYRK3, CLK1, CLK2, CLK4, GSK-3α, and GSK-3β, respectively.

Format & Storage
Format	Solid
Color	Off-white to yellow
Purity	98.12%
Shipping	Room temperature in the continental U.S. Other areas may vary.
Storage	Powder: -20°C, 3 years; 4°C, 2 years In solvent: -80°C, 6 months; -20°C, 1 month
Solubility Overview	Soluble in DMSO

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