Dinaciclib

Dinaciclib

Cat. No.: DIA-0230976

Size: 50 mg Size: 500 mg Size: Customer Size
Product Information
CAS No. 779353-01-4
Synonyms SCH 727965, SCH727965
Chemical Name 2-[(2S)-1-[3-ethyl-7-[(1-oxidopyridin-1-ium-3-yl)methylamino]pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-2-yl]ethanol
Formula C21H28N6O2
Molecular Weight 396.49
PubChem CID 46926350
SMILES CCC1=C2N=C(C=C(N2N=C1)NCC3=C[N+](=CC=C3)[O-])N4CCCC[C@H]4CCO
Product Description Novel, potent, selective cyclin-dependent kinase (CDK) inhibitor displaying selectivity for CDK1, CDK2, CDK5 and CDK9 (IC50 values are 3, 1, 1 and 4 nM respectively). Potent DNA replication inhibitor that blocks thymidine incorporation in A2780 ovarian cancer cells (IC50 = 4 nM).
Format & Storage
Format Solid
Purity > 98%
Source Synthetic
Shipping Shipped at room temperature.
Storage Store at -20 °C. Store under desiccating conditions.
Solubility Overview Soluble in DMSO to 50 mM
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