CYC116

Inquiry

Cat. No.: DIA-0231026

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	693228-63-6
Formula	C₁₈H₂₀N₆OS
Molecular Weight	368.46
SMILES	CC1=C(SC(=N1)N)C2=NC(=NC=C2)NC3=CC=C(C=C3)N4CCOCC4
Product Description	CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3α/β, CK2, Plk1 and SAPK2A. Phase 1.

Format & Storage
Purity	> 99%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

All of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.