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Cat. No.: DIA-0231082
| Product Information | |
|---|---|
| CAS No. | 252917-06-9 |
| Chemical Name | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
| Formula | C22H18Cl2N8 |
| Molecular Weight | 465.34 |
| PubChem CID | 9956119 |
| SMILES | CC1=CN=C(N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N |
| Target | Cdks |
| Product Description | CHIR-99021 (CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3β compared to CDKs. |
| Format & Storage | |
|---|---|
| Format | Liquid |
| Purity | > 98% |
| Source | Synthetic |
| Shipping | Shipped on dry ice. |
| Storage | Store at -20 °C. Store under desiccating conditions. The product can be stored for up to 12 months. |
| Solubility Overview | Soluble in DMSO to 100 mM |
Ace Therapeutics has a team of wellknown experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
