CBL0137 (CBL-0137)

CBL0137 (CBL-0137)

Cat. No.: DIA-0231109

Size: 50 mg Size: 500 mg Size: Customer Size
Product Information
CAS No. 1197397-89-9
Synonyms CBLC137, Curaxin 137
Formula C21H25ClN2O2
Molecular Weight 372.89
SMILES Cl.CC(C)NCC[N]1C2=C(C=C(C=C2)C(C)=O)C3=C1C=CC(=C3)C(C)=O
Product Description CBL0137(CBL-0137) activates p53 and inhibits NF-kB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It also inhibits histone chaperone FACT (facilitates chromatin transcription complex).
Format & Storage
Purity > 98%
Shipping Shipped on dry ice.
Storage Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview Soluble in DMSO
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