Cat. No.: DIA-0231109
Product Information | |
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CAS No. | 1197397-89-9 |
Synonyms | CBLC137, Curaxin 137 |
Formula | C21H25ClN2O2 |
Molecular Weight | 372.89 |
SMILES | Cl.CC(C)NCC[N]1C2=C(C=C(C=C2)C(C)=O)C3=C1C=CC(=C3)C(C)=O |
Product Description | CBL0137(CBL-0137) activates p53 and inhibits NF-kB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It also inhibits histone chaperone FACT (facilitates chromatin transcription complex). |
Format & Storage | |
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Purity | > 98% |
Shipping | Shipped on dry ice. |
Storage | Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month |
Solubility Overview | Soluble in DMSO |
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