Cat. No.: DMM-001201
| Status | Age | Sex |
|---|---|---|
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| Product Overview | |
|---|---|
| Model Description | The Irs1 gene is located on mouse chromosome 1. Two exons are identified, with the ATG start codon in exon 1 and the TAG stop codon in exon 1. Exon 1 will be selected as target site. Cas9 and gRNA will be co-injected into fertilized eggs for KO mouse production. |
| Strain Name | C57BL/6N-Irs1em1 |
| Background Strain | C57BL/6N |
| SPF | Yes |
| Genetic Modification | Conventional knockout |
| Research Application | Diabetes |
| Sperm Quality Evaluation | Pre-cryopreservation: Measurement of sperm concentration, determination of sperm viability. Post-cryopreservation: A vial of cryopreserved sperms is selected for in-vitro fertilization from each batch. |
| Target Information | |
|---|---|
| Target Name | Irs1 |
| Synonyms | IR, IRS-1 |
| Gene ID | 16367 |
