Cat. No.: DMM-001167
| Status | Age | Sex |
|---|---|---|
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| Product Overview | |
|---|---|
| Model Description | The Gzmb gene is located on mouse chromosome 14. Five exons are identified, with the ATG start codon in exon 1 and the TAA stop codon in exon 5. Exon 1~5 will be selected as target site. Cas9 and gRNA will be co-injected into fertilized eggs for KO mouse production. |
| Strain Name | C57BL/6J-Gzmbem1 |
| Background Strain | C57BL/6J |
| SPF | Yes |
| Genetic Modification | Conventional knockout |
| Research Application | Diabetes |
| Sperm Quality Evaluation | Pre-cryopreservation: Measurement of sperm concentration, determination of sperm viability. Post-cryopreservation: A vial of cryopreserved sperms is selected for in-vitro fertilization from each batch. |
| Target Information | |
|---|---|
| Target Name | Gzmb |
| Synonyms | AI553453, CCP, CCP-1/C1, CCP-1/C11, CCP1, Ctl, Ctla, Ctla-1, Ctla1, GZB |
| Gene ID | 14939 |
