Cat. No.: DMM-001064
| Status | Age | Sex |
|---|---|---|
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| Product Overview | |
|---|---|
| Model Description | A IRES-iCre expression cassette was knocked into the Glp1r gene stop codon site. |
| Strain Name | C57BL/6J-Glp1rem1(IRES-iCre) |
| Background Strain | C57BL/6J |
| SPF | Yes |
| Research Application | Cre recombinase tool; When crossed with a strain carrying a gene flanked by loxP sites; the flanked gene will be removed in cells expressing cre. GLP1R encodes a receptor present on many cell types including pancreatic β cells; subsets of neurons in the central nervous system; as well as a subset of vagal sensory neurons in the gastrointestinal tract. |
| Target Information | |
|---|---|
| Target Name | Glp1r |
| Synonyms | GLP-1R, GLP1Rc |
| Gene ID | 14652 |
