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Cat. No.: DMM-001064
| Status | Age | Sex |
|---|---|---|
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| Product Overview | |
|---|---|
| Model Description | A IRES-iCre expression cassette was knocked into the Glp1r gene stop codon site. |
| Strain Name | C57BL/6J-Glp1rem1(IRES-iCre) |
| Background Strain | C57BL/6J |
| SPF | Yes |
| Research Application | Cre recombinase tool; When crossed with a strain carrying a gene flanked by loxP sites; the flanked gene will be removed in cells expressing cre. GLP1R encodes a receptor present on many cell types including pancreatic β cells; subsets of neurons in the central nervous system; as well as a subset of vagal sensory neurons in the gastrointestinal tract. |
| Target Information | |
|---|---|
| Target Name | Glp1r |
| Synonyms | GLP-1R, GLP1Rc |
| Gene ID | 14652 |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
