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Cat. No.: DMM-001010
| Status | Age | Sex |
|---|---|---|
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| Product Overview | |
|---|---|
| Model Description | Exon 3 of Cckbr gene was deleted to generate Cckbr knockout mice. |
| Strain Name | C57BL/6J-Cckbrem1 |
| Background Strain | C57BL/6J |
| SPF | Yes |
| Research Application | This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK); regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor; which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. |
| Target Information | |
|---|---|
| Target Name | Cckbr |
| Synonyms | CCK2R, CCK-BR, CCK2-R, CCKR-2 |
| Gene ID | 12426 |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
