Cat. No.: DMM-001010
| Status | Age | Sex |
|---|---|---|
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| Product Overview | |
|---|---|
| Model Description | Exon 3 of Cckbr gene was deleted to generate Cckbr knockout mice. |
| Strain Name | C57BL/6J-Cckbrem1 |
| Background Strain | C57BL/6J |
| SPF | Yes |
| Research Application | This gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK); regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor; which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. |
| Target Information | |
|---|---|
| Target Name | Cckbr |
| Synonyms | CCK2R, CCK-BR, CCK2-R, CCKR-2 |
| Gene ID | 12426 |
