Buparlisib (BKM120, NVP-BKM120)

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Cat. No.: DIA-0231139

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	944396-07-0
Formula	C₁₈H₂₁F₃N₆O₂
Molecular Weight	410.39
SMILES	NC1=CC(=C(C=N1)C2=NC(=NC(=C2)N3CCOCC3)N4CCOCC4)C(F)(F)F
Product Description	Buparlisib (BKM120, NVP-BKM120) is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM in cell-free assays, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. Phase 2.

Format & Storage
Purity	> 98%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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