Bioymifi

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Cat. No.: DIA-0231165

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	1420071-30-2
Formula	C₂₂H₁₂BrN₃O₄S
Molecular Weight	494.32
SMILES	BrC1=CC=C(C=C1)N2C(=N)S\C(=C/C3=CC=C(O3)C4=CC=C5C(=O)NC(=O)C5=C4)C2=O
Target	DR5
Product Description	Bioymifi, a small-molecule death receptor 5 (DR5) agonist, binds to the extracellular domain(ECD) of DR5 with a Kd of 1.2 μM but showed little binding affinity to the DR4 ECD. It induces DR5 clustering and aggregation, leading to apoptosis.

Format & Storage
Purity	> 99%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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