B-Raf IN 1

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Cat. No.: DIA-0231147

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	950736-05-7
Formula	C₂₉H₂₄F₃N₅O
Molecular Weight	515.53
SMILES	CN(C)CC1=CC=C(C=C1)C2=C3N=CC=C([N]3N=C2)C4=CC(=CC=C4)NC(=O)C5=CC=CC(=C5)C(F)(F)F
Target	PKCα, IKKβ, and PI3Kα.
Product Description	B-Raf IN 1 is an inhibitor of Raf wih IC50 values of 24 nM and 25 nM for B-Raf and C-Raf respectively. It is selective over 13 other kinases, including PKCα, IKKβ, and PI3Kα.

Format & Storage
Purity	> 99%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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