Axitinib

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Cat. No.: DIA-0231221

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	319460-85-0
Synonyms	AG 013736
Formula	C₂₂H₁₈N₄OS
Molecular Weight	386.47
SMILES	CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=N[NH]3)\C=C\C4=CC=CC=N4
Target	VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit
Product Description	Axitinib is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively.

Format & Storage
Purity	> 99%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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