AMG-221

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Cat. No.: DIA-0243095

Size: 10 mg Size: 25 mg Size: 50 mg Size: 100 mg Size: Customer Size

Product Information
CAS No.	1095565-81-3
Formula	C₁₄H₂₂N₂OS
Molecular Weight	266.40
SMILES	O=C1N=C(N[C@@H]2[C@@](C3)([H])CC[C@@]3([H])C2)S[C@@]1(C)C(C)C
Target	11β-HSD
Product Description	AMG-221 is an inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) with a Ki of 12.8 nM in vitro biochemical scintillation proximity assay (SPA) and an IC50 of 10.1 nM in cell-based assays. AMG-221 can be used for the research of type 2 diabetes.

Format & Storage
Shipping	Room temperature in the continental U.S. Other areas may vary.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

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