Alvelestat (AZD9668)

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Cat. No.: DIA-0231288

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	848141-11-7
Synonyms	Avelestat
Formula	C₂₄H₂₀F₃N₅O₄S
Molecular Weight	545.53
SMILES	C[N]1N=CC=C1C2=CN(C(=O)C(=C2)C(=O)NCC3=NC=C(C=C3)[S](C)(=O)=O)C4=CC=CC(=C4)C(F)(F)F
Product Description	Alvelestat (AZD9668) is an oral, highly selective inhibitor of neutrophil elastase (NE) with IC50 and Ki of 12 nM and 9.4 nM, at least 600-fold more selective over other serine proteases.

Format & Storage
Format	Solid
Purity	> 99%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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