Afuresertib (GSK2110183)

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Cat. No.: DIA-0231320

Size: 50 mg Size: 500 mg Size: Customer Size

Product Information
CAS No.	1047644-62-1
Formula	C₁₈H₁₇Cl₂FN₄OS
Molecular Weight	427.32
SMILES	C[N]1N=CC(=C1C2=C(Cl)SC(=C2)C(=O)NC(CN)CC3=CC=CC(=C3)F)Cl
Product Description	Afuresertib (GSK2110183) is a potent, orally bioavailable Akt inhibitor with Ki of 0.08 nM, 2 nM, and 2.6 nM for Akt1, Akt2, and Akt3, respectively. Phase 2.

Format & Storage
Purity	> 97%
Shipping	Shipped on dry ice.
Storage	Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview	Soluble in DMSO

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