Cat. No.: DIA-0231362
Product Information | |
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CAS No. | 5142-23-4 |
Synonyms | NSC 66389 |
Formula | C6H7N5 |
Molecular Weight | 149.15 |
SMILES | C[N]1C=NC(=C2N=CN=C12)N |
Target | Vps34 and PI3Kγ |
Product Description | 3-Methyladenine (3-MA) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM in HeLa cells blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation. |
Format & Storage | |
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Purity | > 98% |
Shipping | Shipped on dry ice. |
Storage | Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month |
Solubility Overview | Soluble in DMSO |