3-Methyladenine (3-MA)

3-Methyladenine (3-MA)

Cat. No.: DIA-0231362

Size: 50 mg Size: 500 mg Size: Customer Size
Product Information
CAS No. 5142-23-4
Synonyms NSC 66389
Formula C6H7N5
Molecular Weight 149.15
SMILES C[N]1C=NC(=C2N=CN=C12)N
Target Vps34 and PI3Kγ
Product Description 3-Methyladenine (3-MA) is a selective PI3K inhibitor for Vps34 and PI3Kγ with IC50 of 25 μM and 60 μM in HeLa cells blocks class I PI3K consistently, whereas suppression of class III PI3K is transient, and also blocks autophagosome formation.
Format & Storage
Purity > 98%
Shipping Shipped on dry ice.
Storage Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month
Solubility Overview Soluble in DMSO
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