Cat. No.: DIA-0231373
| Product Information | |
|---|---|
| CAS No. | 144707-18-6 |
| Synonyms | 2',3',4'-trihydroxy flavone |
| Formula | C15H10O5 |
| Molecular Weight | 270.24 |
| SMILES | OC1=CC=C(C(=C1O)O)C2=CC(=O)C3=CC=CC=C3O2 |
| Target | Axl, IRAK4, ROS1, MLK4, GSK3β, RET, KDR and PI3Kα |
| Product Description | 2-D08 is a cell permeable, mechanistically unique inhibitor of protein sumoylation. It is also inhibits Axl, IRAK4, ROS1, MLK4, GSK3β, RET, KDR and PI3Kα with IC50 values of 0.49, 3.9, 5.3, 9.8, 11, 11, 17 and 35 nM respectively in biochemical assays. |
| Format & Storage | |
|---|---|
| Purity | > 97% |
| Shipping | Shipped on dry ice. |
| Storage | Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month |
| Solubility Overview | Soluble in DMSO |
