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Cat. No.: DIA-0231373
| Product Information | |
|---|---|
| CAS No. | 144707-18-6 |
| Synonyms | 2',3',4'-trihydroxy flavone |
| Formula | C15H10O5 |
| Molecular Weight | 270.24 |
| SMILES | OC1=CC=C(C(=C1O)O)C2=CC(=O)C3=CC=CC=C3O2 |
| Target | Axl, IRAK4, ROS1, MLK4, GSK3β, RET, KDR and PI3Kα |
| Product Description | 2-D08 is a cell permeable, mechanistically unique inhibitor of protein sumoylation. It is also inhibits Axl, IRAK4, ROS1, MLK4, GSK3β, RET, KDR and PI3Kα with IC50 values of 0.49, 3.9, 5.3, 9.8, 11, 11, 17 and 35 nM respectively in biochemical assays. |
| Format & Storage | |
|---|---|
| Purity | > 97% |
| Shipping | Shipped on dry ice. |
| Storage | Powder: -20 °C, 3 years; 4 °C, 2 years In solvent: -80 °C, 6 months; -20 °C, 1 month |
| Solubility Overview | Soluble in DMSO |
Ace Therapeutics has a team of experts in the field of endocrine and metabolic research, aiming to provide innovative preclinical contract research solutions to cope with diabetes and its complications. We provide customized solutions and technical support, enabling the transformation of promising concepts into innovative treatments, thus accelerating the drug development process of diabetes.
