Zoniporide hydrochloride hydrate

Cat. No: CDIA-0637

CAS. No.: 863406-85-3

Synonyms: CP-597396 hydrochloride hydrate

Size: 5 mg

Price: Inquiry

Product Details
Formula	C17H19ClN6O2
Molecular Weight	374.82
Appearance	Solid
Purity	≥99.0%
Smiles String	O=C(C1=C(C2CC2)N(C3=C4C=CC=NC4=CC=C3)N=C1)NC(N)=N.[H]Cl.[H]O[H]

Storage & Handling
Shipping	Room temperature.
Storage	4 °C, sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)

Description

Zoniporide (CP-597396) hydrochloride hydrate is a potent and selective inhibitor of sodium-hydrogen exchanger type 1 (NHE-1). Zoniporide hydrochloride hydrate inhibits human NHE-1 (IC50=14 nM), and has >150-fold selectivity versus other NHE isoforms. Zoniporide hydrochloride hydrate potently inhibits ex vivo NHE-1-dependent swelling of human platelets (IC50=59 nM).

! For research use only. Not intended for any clinical use.