YS-49

Cat. No: CDIA-0231

CAS. No.: 132836-42-1

Size: 1 mg

Price: Inquiry

Product Details
Formula	C20H20BrNO2
Molecular Weight	386.28
Appearance	Solid
Purity	99.92%
Smiles String	OC1=CC2=C(C(CC3=C4C=CC=CC4=CC=C3)NCC2)C=C1O.[H]Br

Storage & Handling
Shipping	Room temperature.
Storage	4 °C, stored under nitrogen *In solvent : -80 °C, 6 months; -20 °C, 1 month (stored under nitrogen)

Description

YS-49 is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibits angiotensin II (Ang II)-stimulated proliferation of VSMCs via induction of heme oxygenase (HO)-1. YS-49 is also an isoquinoline compound alkaloid, has a strong positive inotropic action through activation of cardiac β-adrenoceptors.

! For research use only. Not intended for any clinical use.