VU0134992 hydrochloride

Cat. No: CDIA-0620

CAS. No.: 1052515-91-9

Size: 5 mg

Price: Inquiry

Product Details
Formula	C20H32BrClN2O2
Molecular Weight	447.84
Appearance	Solid
Purity	98.34%
Smiles String	O=C(NC1CC(C)(C)NC(C)(C)C1)COC2=CC=C(C(C)C)C=C2Br.[H]Cl

Storage & Handling
Shipping	Room temperature.
Storage	4 °C, sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)

Description

VU0134992 hydrochloride is the first subtype-preferring, orally active and selective Kir4.1 potassium channel pore blocker, with an IC50 of 0.97 µM. VU0134992 hydrochloride is 9-fold selective for homomeric Kir4.1 over Kir4.1/5.1 concatemeric channels (IC50=9 µM) at -120 mV.

! For research use only. Not intended for any clinical use.