Trimetazidine-d8 (di hydrochloride)
Online Inquiry
* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Trimetazidine-d8 (di hydrochloride)

Cat. No: CDIA-1012
CAS. No.: 1219795-37-5
Size: 5 mg
Price: Inquiry
Product Details
Formula C14H16D8Cl2N2O3
Molecular Weight 347.31
Appearance Solid
Purity ≥99.0%
Smiles String COC1=C(CN2C([2H])(C([2H])(NC([2H])(C2([2H])[2H])[2H])[2H])[2H])C=CC(OC)=C1OC.Cl.Cl
Storage & Handling
Shipping Room temperature.
Storage -20 °C, protect from light, stored under nitrogen *In solvent : -80 °C, 6 months; -20 °C, 1 month (protect from light, stored under nitrogen)

Description

Trimetazidine-d8 (dihydrochloride) is the deuterium labeled Trimetazidine dihydrochloride. Trimetazidine dihydrochloride is a selective long chain 3-ketoyl coenzyme A thiolase inhibitor with an IC50 of 75 nM, which can inhibit β-oxidation of free fatty acid (FFA). Trimetazidine dihydrochloride is an effective antianginal agent and a cytoprotective drug, has anti-oxidant, anti-inflammatory, antinociceptive and gastroprotective properties. Trimetazidine dihydrochloride triggers autophagy. Trimetazidine dihydrochloride is also a 3-hydroxyacyl-CoA dehydrogenase (HADHA) inhibitor.

! For research use only. Not intended for any clinical use.