Tovinontrine
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Tovinontrine

Cat. No: CDIA-0483
CAS. No.: 2062661-53-2
Synonyms: IMR-687
Size: 5 mg
Price: Inquiry
Product Details
Formula C21H26N6O2
Molecular Weight 394.47
Appearance Solid
Purity 99.83%
Smiles String O=C1C2=CN=C(C3CCOCC3)N2C=C([[email protected]@H]4CN(CC5=NC=CC=N5)C[[email protected]]4C)N1
Storage & Handling
Shipping Room temperature.
Storage Powder -20 °C/3 years, 4 °C/2 years

Description

Tovinontrine (IMR-687) is a highly potent and selective phosphodiesterase-9 (PDE9) inhibitor specifically for the treatment of sickle cell disease. IC50s are 8.19 nM and 9.99 nM for PDE9A1 and PDE9A2, respectively.

! For research use only. Not intended for any clinical use.