Basic Research

Online Inquiry

* First Name

* Last Name

Phone

* Business Email

Company/Institution

Job Title

* Services or Products of Interest

When do you expect your project to start?

Project Description

* Please note that all of our services and products are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.

Sirt1-Flox

Cat. No: CDM0002

Nomenclature: C57BL/6J-Sirt1^tm1(flox)

Strain State: Embryo cryopreservation

Gene Summary
Human Ortholog	SIRT1
MGI ID	2135607
Gene ID	93759
Target Name	Sirt1
Synonyms	Sir2, Sir2a, SIR2L1, AA673258, Sir2alpha

Model Description
Description	These mice carry loxP sites flanking exon3 of Sirt1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Sirt1 gene.
Disease Connection	Fatty Liver Disease
Phenotype(s)	5305254
Note	The expected phenotype(s) may be observed in the above-mentioned mice that bred with Alb1-cre mice.

! For research use only. Not intended for any clinical use.