Simvastatin acid

Cat. No: CDIA-1784

CAS. No.: 121009-77-6

Synonyms: Tenivastatin

Size: 50 mg

Price: Inquiry

Product Details
Formula	C25H40O6
Molecular Weight	436.58
Smiles String	O=C(C[[email protected]@H](C[[email protected]@H](CC[[email protected]]1[[email protected]](C=CC2=C[[email protected]@H](C[[email protected]@H]([[email protected]]12[H])OC(C(C)(CC)C)=O)C)C)O)O)O

Storage & Handling
Shipping	Room temperature.
Storage	Please refer to the instruction manual.

Description

Simvastatin acid (Tenivastatin), a hydrolysate of Simvastatin (HY-17502), is a HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.

! For research use only. Not intended for any clinical use.