Simvastatin acid ammonium

Cat. No: CDIA-0526

CAS. No.: 139893-43-9

Synonyms: Tenivastatin ammonium

Size: 5 mg

Price: Inquiry

Product Details
Formula	C25H43NO6
Molecular Weight	453.61
Appearance	Solid
Purity	99.32%
Smiles String	O=C(C[[email protected]@H](C[[email protected]@H](CC[[email protected]]1[[email protected]](C=CC2=C[[email protected]@H](C[[email protected]@H]([[email protected]]12[H])OC(C(C)(CC)C)=O)C)C)O)O)[O-].[NH4+]

Storage & Handling
Shipping	Room temperature.
Storage	4 °C, sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)

Description

Simvastatin acid (Tenivastatin) ammonium is a potent HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid ammonium reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid ammonium can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.

! For research use only. Not intended for any clinical use.