Sacubitril/Valsartan

Cat. No: CDIA-0193

CAS. No.: 936623-90-4

Synonyms: LCZ696

Size: 1 mg

Price: Inquiry

Product Details
Formula	C48H55N6Na3O8.2.5H2O
Molecular Weight	957.99
Appearance	Solid
Purity	99.99%
Smiles String	O=C(CCC(O[Na])=O)N([[email protected]](CC(C=C1)=CC=C1C2=CC=CC=C2)C[[email protected]@H](C)C(OCC)=O)[H].O=C(O[Na])[[email protected]@H](N(C(CCCC)=O)CC3=CC=C(C4=CC=CC=C4C5=NN=NN5[Na])C=C3)C(C)C.[2.5H2O]

Storage & Handling
Shipping	Room temperature.
Storage	4 °C, sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)

Description

Sacubitril/Valsartan (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure. Sacubitril/Valsartan ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis.

! For research use only. Not intended for any clinical use.