RPR-260243

Cat. No: CDIA-0827

CAS. No.: 668463-35-2

Size: 5 mg

Price: Inquiry

Product Details
Formula	C28H25F3N2O4
Molecular Weight	510.50
Appearance	Solid
Purity	99.37%
Smiles String	O=C([[email protected]]1CN(CC#CC2=CC(F)=CC(F)=C2F)CC[[email protected]]1CCC(C3=CC=NC4=CC=C(OC)C=C34)=O)O

Storage & Handling
Shipping	Room temperature.
Storage Powder	-20 °C/3 years, 4 °C/2 years

Description

RPR-260243, a potent activator of human ether-a-go-go-related gene (hERG), slows deactivation and attenuates inactivation of hERG1 channels. RPR260243-modified HERG currents are inhibited by Dofetilide (IC50=58 nM). RPR260243 displays no activator-like effects on other voltage-dependent ion channels, including the closely related ERG3 K+ channel.

! For research use only. Not intended for any clinical use.