Rosuvastatin sodium

Cat. No: CDIA-0851

CAS. No.: 147098-18-8

Synonyms: ZD 4522 Sodium; X-Plended Sodium; Crestor Sodium

Size: 5 mg

Price: Inquiry

Product Details
Formula	C22H27FN3NaO6S
Molecular Weight	503.52
Appearance	Solid
Purity	99.76%
Smiles String	O=C(O[Na])C[[email protected]](O)C[[email protected]](O)/C=C/C1=C(C(C)C)N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2

Storage & Handling
Shipping	Room temperature.
Storage	4 °C, sealed storage, away from moisture and light *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture and light)

Description

Rosuvastatin Sodium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Sodium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Sodium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Sodium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.

! For research use only. Not intended for any clinical use.