Rosuvastatin calcium

Cat. No: CDIA-0039

CAS. No.: 147098-20-2

Synonyms: Rosuvastatin hemicalcium; ZD 4522 Calcium

Size: 1 mg

Price: Inquiry

Product Details
Formula	C22H27Ca0.5FN3O6S
Molecular Weight	500.57
Appearance	Solid
Purity	99.94%
Smiles String	O=C([O-])C[[email protected]](O)C[[email protected]](O)/C=C/C1=C(C(C)C)N=C(N(C)S(=O)(C)=O)N=C1C2=CC=C(F)C=C2.[0.5Ca2+]

Storage & Handling
Shipping	Room temperature.
Storage	4 °C, sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)

Description

Rosuvastatin Calcium is a competitive HMG-CoA reductase (HMGCR) inhibitor, with an IC50 of 11 nM. Rosuvastatin Calcium potently blocks hERG current with an IC50 of 195 nM. Rosuvastatin Calcium reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin Calcium effectively lowers low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.

! For research use only. Not intended for any clinical use.