Rostafuroxin
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Rostafuroxin

Cat. No: CDIA-0406
CAS. No.: 156722-18-8
Synonyms: PST 2238
Size: 1 mg
Price: Inquiry
Product Details
Formula C23H34O4
Molecular Weight 374.51
Appearance Solid
Purity 98.00%
Smiles String O[[email protected]]([[email protected]@](CC[[email protected]@]1([H])[[email protected]@]2(CC[[email protected]](O)C1)C)([H])[[email protected]]2([H])CC3)(CC[[email protected]@]4(C5=COC=C5)O)[[email protected]]34C
Storage & Handling
Shipping Room temperature.
Storage Powder -20 °C/3 years, 4 °C/2 years

Description

Rostafuroxin (PST 2238), a digitoxigenin derivative, is an orally active and potent Na+,K+-ATPase (ATP1A1) antognist. Rostafuroxin binds specifically to the ATP1A1 extracellular domain and blocks respiratory syncytial virus (RSV)-triggered EGFR Tyr845 phosphorylation. Rostafuroxin has antihypertensive and anti-RSV activity.

! For research use only. Not intended for any clinical use.