Rodatristat
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Rodatristat

Cat. No: CDIA-1315
CAS. No.: 1673568-73-4
Synonyms: KAR5417
Size: 50 mg
Price: Inquiry
Product Details
Formula C27H27ClF3N5O3
Molecular Weight 561.98
Smiles String O=C([[email protected]]1NCC2(CCN(C3=NC(N)=NC(O[[email protected]](C4=CC=C(Cl)C=C4C5=CC=CC=C5)C(F)(F)F)=C3)CC2)C1)O
Storage & Handling
Shipping Room temperature.
Storage Please refer to the instruction manual.

Description

Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC50s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice.

! For research use only. Not intended for any clinical use.