Ro 46-8443

Cat. No: CDIA-1429

CAS. No.: 175556-12-4

Size: 50 mg

Price: Inquiry

Product Details
Formula	C31H35N3O8S
Molecular Weight	609.69
Appearance	Solid
Purity	99.24%
Smiles String	O=S(C1=CC=C(C(C)(C)C)C=C1)(NC2=NC(C3=CC=C(OC)C=C3)=NC(OC[[email protected]](O)CO)=C2OC4=CC=CC=C4OC)=O

Storage & Handling
Shipping	Room temperature.
Storage	4 °C, sealed storage, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (sealed storage, away from moisture)

Description

Ro 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. Ro 46-8443 displays an at least 100-fold selectivity for ETB (IC50: 34-69 nM) over ETA receptors (IC50: 6800 nM).

! For research use only. Not intended for any clinical use.