Rilmenidine hemifumarate
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Rilmenidine hemifumarate

Cat. No: CDIA-0644
CAS. No.: 207572-68-7
Size: 5 mg
Price: Inquiry
Product Details
Formula C10H16N2O.1/2C4H4O4
Molecular Weight 238.28
Appearance Solid
Purity 99.78%
Smiles String O=C(O)/C=C/C(O)=O.C1(NC(C2CC2)C3CC3)=NCCO1.[0.5]
Storage & Handling
Shipping Room temperature.
Storage -20 °C, stored under nitrogen, away from moisture *In solvent : -80 °C, 6 months; -20 °C, 1 month (stored under nitrogen, away from moisture)

Description

Rilmenidine hemifumarate, an innovative antihypertensive agent, is an orally active, selective I1 imidazoline receptor agonist. Rilmenidine hemifumarate is an alpha 2-adrenoceptor agonist. Rilmenidine hemifumarate induces autophagy. Rilmenidine hemifumarate acts both centrally by reducing sympathetic overactivity and in the kidney by inhibiting the Na+/H+ antiport. Rilmenidine hemifumarate modulates proliferation and stimulates the proapoptotic protein Bax thus inducing the perturbation of the mitochondrial pathway and apoptosis in human leukemic K562 cells .

! For research use only. Not intended for any clinical use.